Spread the love
  •  
  •  
  •  
  •  
  •  
  •  
  •  

Columbia Engineers develop the smallest single-chip system

Columbia Engineers develop the smallest single-chip system that is a complete functioning electronic circuit; implantable chips visible only in a microscope point the way to developing chips that can be injected into the body with a hypodermic needle to monitor medical conditions

New York, NY—May 12, 2021—Widely used to monitor and map biological signals, to support and enhance physiological functions, and to treat diseases, implantable medical devices are transforming healthcare and improving the quality of life for millions of people. Researchers are increasingly interested in designing wireless, miniaturized implantable medical devices for in vivo and in situ physiological monitoring. These devices could be used to monitor physiological conditions, such as temperature, blood pressure, glucose, and respiration for both diagnostic and therapeutic procedures.

To date, conventional implanted electronics have been highly volume-inefficient—they generally require multiple chips, packaging, wires, and external transducers, and batteries are often needed for energy storage. A constant trend in electronics has been tighter integration of electronic components, often moving more and more functions onto the integrated circuit itself.

Researchers at Columbia Engineering report that they have built what they say is the world’s smallest single-chip system, consuming a total volume of less than 0.1 mm3. The system is as small as a dust mite and visible only under a microscope. In order to achieve this, the team used ultrasound to both power and communicate with the device wirelessly. The study was published online May 7 in Science Advances.

“We wanted to see how far we could push the limits on how small a functioning chip we could make,” said the study’s leader Ken Shepard, Lau Family professor of electrical engineering and professor of biomedical engineering. “This is a new idea of ‘chip as system’—this is a chip that alone, with nothing else, is a complete functioning electronic system. This should be revolutionary for developing wireless, miniaturized implantable medical devices that can sense different things, be used in clinical applications, and eventually approved for human use.”

The team also included Elisa Konofagou, Robert and Margaret Hariri Professor of Biomedical engineering and professor of radiology, as well as Stephen A. Lee, PhD student in the Konofagou lab who assisted in the animal studies.

The design was done by doctoral student Chen Shi, who is the first author of the study. Shi’s design is unique in its volumetric efficiency, the amount of function that is contained in a given amount of volume. Traditional RF communications links are not possible for a device this small because the wavelength of the electromagnetic wave is too large relative to the size of the device. Because the wavelengths for ultrasound are much smaller at a given frequency because the speed of sound is so much less than the speed of light, the team used ultrasound to both power and communicate with the device wirelessly. They fabricated the “antenna” for communicating and powering with ultrasound directly on top of the chip.

The chip, which is the entire implantable/injectable mote with no additional packaging, was fabricated at the Taiwan Semiconductor Manufacturing Company with additional process modifications performed in the Columbia Nano Initiative cleanroom and the City University of New York Advanced Science Research Center (ASRC) Nanofabrication Facility.

Shepard commented, “This is a nice example of ‘more than Moore’ technology—we introduced new materials onto standard complementary metal-oxide-semiconductor to provide new function. In this case, we added piezoelectric materials directly onto the integrated circuit to transducer acoustic energy to electrical energy.”

Konofagou added, “Ultrasound is continuing to grow in clinical importance as new tools and techniques become available. This work continues this trend.”

The team’s goal is to develop chips that can be injected into the body with a hypodermic needle and then communicate back out of the body using ultrasound, providing information about something they measure locally. The current devices measure body temperature, but there are many more possibilities the team is working on.

###

Columbia Engineering

Columbia Engineering, based in New York City, is one of the top engineering schools in the U.S. and one of the oldest in the nation. Also known as The Fu Foundation School of Engineering and Applied Science, the School expands knowledge and advances technology through the pioneering research of its more than 220 faculty, while educating undergraduate and graduate students in a collaborative environment to become leaders informed by a firm foundation in engineering. The School’s faculty are at the center of the University’s cross-disciplinary research, contributing to the Data Science Institute, Earth Institute, Zuckerman Mind Brain Behavior Institute, Precision Medicine Initiative, and the Columbia Nano Initiative. Guided by its strategic vision, “Columbia Engineering for Humanity,” the School aims to translate ideas into innovations that foster a sustainable, healthy, secure, connected, and creative humanity.

Fount from: https://www.engineering.columbia.edu/press-releases/shepard-injectable-chips-monitor-body-processes?fbclid=IwAR2o6gyklCNlSjZ_oseSCpXrF6LG-Hi9BdV036pJ5mcSgSiSKijT3gq1thM

  •  
  •  
  •  
  •  
  •  
  •  

6 thoughts on “Columbia Engineers develop the smallest single-chip system

  1. I really wanted to send a simple word to be able to appreciate you for all of the remarkable secrets you are writing here. My incredibly long internet investigation has finally been paid with good suggestions to talk about with my company. I ‘d tell you that many of us website visitors actually are unequivocally fortunate to live in a really good place with so many wonderful individuals with insightful strategies. I feel extremely fortunate to have seen your webpage and look forward to plenty of more cool minutes reading here. Thank you once again for everything.

  2. Thanks a ton for your post. I would like to say that the cost of car insurance differs a lot from one insurance plan to another, given that there are so many different facets which bring about the overall cost. As an example, the brand name of the car or truck will have a large bearing on the charge. A reliable aged family car will have a less expensive premium than a flashy expensive car.

  3. Simply want to say your article is as surprising. The clearness in your submit is just nice and i could assume you are an expert in this subject. Fine together with your permission allow me to grasp your RSS feed to stay updated with imminent post. Thank you one million and please keep up the enjoyable work.

  4. Hello there, just became aware of your blog through Google, and found that it is truly informative. I抦 gonna watch out for brussels. I will be grateful if you continue this in future. Lots of people will be benefited from your writing. Cheers!

  5. Thanks for the tips you have contributed here. Something important I would like to state is that personal computer memory specifications generally increase along with other innovations in the technologies. For instance, when new generations of processor chips are brought to the market, there is certainly usually an equivalent increase in the dimensions preferences of both the computer memory and hard drive space. This is because the application operated through these processor chips will inevitably surge in power to take advantage of the new technological know-how.

Leave a Reply

Your email address will not be published. Required fields are marked *

You may use these HTML tags and attributes:

<a href="" title=""> <abbr title=""> <acronym title=""> <b> <blockquote cite=""> <cite> <code> <del datetime=""> <em> <i> <q cite=""> <s> <strike> <strong>